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Identification and Structural Characterization of Novel Chondroitin/Dermatan Sulfate Hexassacharide Domains in Human Decorin by Ion Mobility Tandem Mass Spectrometry

Chondroitin sulfate (CS) and dermatan sulfate (DS) are found in nature linked to proteoglycans, most often as hybrid CS/DS chains. In the extracellular matrix, where they are highly expressed, CS/DS are involved in fundamental processes and various pathologies. The structural diversity of CS/DS doma...

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Detalles Bibliográficos
Autores principales: Sarbu, Mirela, Ica, Raluca, Sharon, Edie, Clemmer, David E., Zamfir, Alina D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505904/
https://www.ncbi.nlm.nih.gov/pubmed/36144762
http://dx.doi.org/10.3390/molecules27186026