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PSP-GNM: Predicting Protein Stability Changes upon Point Mutations with a Gaussian Network Model
Understanding the effects of missense mutations on protein stability is a widely acknowledged significant biological problem. Genomic missense mutations may alter one or more amino acids, leading to increased or decreased stability of the encoded proteins. In this study, we describe a novel approach...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505940/ https://www.ncbi.nlm.nih.gov/pubmed/36142614 http://dx.doi.org/10.3390/ijms231810711 |