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Formulation of Modified-Release Bilayer Tablets of Atorvastatin and Ezetimibe: An In-Vitro and In-Vivo Analysis

The objective of this work was to formulate co-loaded bilayer tablets containing ezetimibe (EZB) and atorvastatin (ATC). ATC loaded in the immediate-release (IR) layer is an HMG CoA reductase inhibitor, while EZB, added in the sustained-release (SR) layer, is a lipid-lowering agent. This study was c...

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Detalles Bibliográficos
Autores principales: Mubeen, Iqra, Zaman, Muhammad, Farooq, Muhammad, Mehmood, Asim, Azeez, Fahad Khan, Rehman, Wajiha, Akhtar, Sohail, Chaudhry, Mueen Ahmad, Butt, Muhammad Hammad, Shamim, Qurat-ul-ain, Adnan, Sherjeel, Khan, Muhammad Rizwan, Atta-ur-Rehman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506081/
https://www.ncbi.nlm.nih.gov/pubmed/36145914
http://dx.doi.org/10.3390/polym14183770