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Potential Use of 3D CORAGRAF-Loaded PDGF-BB in PLGA Microsphere Seeded Mesenchymal Stromal Cells in Enhancing the Repair of Calvaria Critical-Size Bone Defect in Rat Model

Our previous study evidenced that the 3D CORAGRAF loaded with PLGA microsphere constitutes PDGF-BB can support cell attachment and proliferation and can induce an osteogenic commitment of mesenchymal stromal cells in the in vitro condition. However, how this construct can perform in pathophysiologic...

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Detalles Bibliográficos
Autores principales: Mohan, Saktiswaren, Karunanithi, Puvanan, Raman Murali, Malliga, Anwar Ayob, Khairul, Megala, Jayaraman, Genasan, Krishnamurithy, Kamarul, Tunku, Balaji Raghavendran, Hanumantha Rao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506139/
https://www.ncbi.nlm.nih.gov/pubmed/36135749
http://dx.doi.org/10.3390/md20090561