Probiotic as Adjuvant Significantly Improves Protection of the Lanzhou Trivalent Rotavirus Vaccine against Heterologous Challenge in a Gnotobiotic Pig Model of Human Rotavirus Infection and Disease

This preclinical study in the gnotobiotic (Gn) pig model of human rotavirus (HRV) infection and disease evaluates the effect of probiotic Lactobacillus rhamnosus GG (LGG) as a mucosal adjuvant on the immunogenicity and cross-protective efficacy of the Lanzhou live oral trivalent (G2, G3, G4) vaccine...

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Detalles Bibliográficos
Autores principales: Parreno, Viviana, Bai, Muqun, Liu, Fangning, Jing, Jiqiang, Olney, Erika, Li, Guohua, Wen, Ke, Yang, Xingdong, Castellucc, Tammy Bui, Kocher, Jacob F., Zhou, Xu, Yuan, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506166/
https://www.ncbi.nlm.nih.gov/pubmed/36146607
http://dx.doi.org/10.3390/vaccines10091529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506166/
https://www.ncbi.nlm.nih.gov/pubmed/36146607
http://dx.doi.org/10.3390/vaccines10091529

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