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Maternal and Fetal PI3K-p110α Deficiency Induces Sex-Specific Changes in Conceptus Growth and Placental Mitochondrial Bioenergetic Reserve in Mice

SIMPLE SUMMARY: The placenta is responsible for materno-fetal resource allocation. Placental insufficiency may disrupt fetal growth trajectory, with negative consequences for maternal and fetal health. By manipulating a growth-controlling protein named PI3K-p110α, this work, performed on mice, shows...

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Detalles Bibliográficos
Autores principales: Pereira-Carvalho, Daniela, Salazar-Petres, Esteban, Lopez-Tello, Jorge, Sferruzzi-Perri, Amanda N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506205/
https://www.ncbi.nlm.nih.gov/pubmed/36136716
http://dx.doi.org/10.3390/vetsci9090501