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PLGA-PVA-PEG Single Emulsion Method as a Candidate for Aminolevulinic Acid (5-ALA) Encapsulation: Laboratory Scaling Up and Stability Evaluation

One of the most widely used molecules used for photodynamic therapy (PDT) is 5-aminolevulinic acid (5-ALA), a precursor in the synthesis of tetrapyrroles such as chlorophyll and heme. The 5-ALA skin permeation is considerably reduced due to its hydrophilic characteristics, decreasing its local bioav...

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Detalles Bibliográficos
Autores principales: da Silva, Geisiane Rosa, dos Santos, Amanda Luizetto, Soares, Andrey Coatrini, dos Santos, Marinalva Cardoso, dos Santos, Sandra Cruz, Ţălu, Ştefan, Rodrigues de Lima, Vânia, Bagnato, Vanderlei Salvador, Sanches, Edgar Aparecido, Inada, Natalia Mayumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506276/
https://www.ncbi.nlm.nih.gov/pubmed/36144765
http://dx.doi.org/10.3390/molecules27186029