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Structural Basis of Artemisinin Binding Sites in Serum Albumin with the Combined Use of NMR and Docking Calculations

Artemisinin is known to bind to the main plasma protein carrier serum albumin (SA); however, there are no atomic level structural data regarding its binding mode with serum albumin. Herein, we employed a combined strategy of saturation transfer difference (STD), transfer nuclear Overhauser effect sp...

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Detalles Bibliográficos
Autores principales: Primikyri, Alexandra, Papamokos, Georgios, Venianakis, Themistoklis, Sakka, Marianna, Kontogianni, Vassiliki G., Gerothanassis, Ioannis P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506303/
https://www.ncbi.nlm.nih.gov/pubmed/36144648
http://dx.doi.org/10.3390/molecules27185912