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The Encapsulation of Citicoline within Solid Lipid Nanoparticles Enhances Its Capability to Counteract the 6-Hydroxydopamine-Induced Cytotoxicity in Human Neuroblastoma SH-SY5Y Cells

(1) Backgrond: Considering the positive effects of citicoline (CIT) in the management of some neurodegenerative diseases, the aim of this work was to develop CIT-Loaded Solid Lipid Nanoparticles (CIT-SLNs) for enhancing the therapeutic use of CIT in parkinsonian syndrome; (2) Methods: CIT-SLNs were...

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Detalles Bibliográficos
Autores principales: Margari, Andrea, Monteduro, Anna Grazia, Rizzato, Silvia, Capobianco, Loredana, Crestini, Alessio, Rivabene, Roberto, Piscopo, Paola, D’Onofrio, Mara, Manzini, Valeria, Trapani, Giuseppe, Quarta, Alessandra, Maruccio, Giuseppe, Ventra, Carmelo, Lieto, Luigi, Trapani, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506317/
https://www.ncbi.nlm.nih.gov/pubmed/36145575
http://dx.doi.org/10.3390/pharmaceutics14091827