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Estrogen Receptor Subtypes Elicit a Distinct Gene Expression Profile of Endothelial-Derived Factors Implicated in Atherosclerotic Plaque Vulnerability

In the presence of established atherosclerosis, estrogens are potentially harmful. MMP-2 and MMP-9, their inhibitors (TIMP-2 and TIMP-1), RANK, RANKL, OPG, MCP-1, lysyl oxidase (LOX), PDGF-β, and ADAMTS-4 play critical roles in plaque instability/rupture. We aimed to investigate (i) the effect of es...

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Detalles Bibliográficos
Autores principales: Nasiri-Ansari, Narjes, Spilioti, Eliana, Kyrou, Ioannis, Kalotychou, Vassiliki, Chatzigeorgiou, Antonios, Sanoudou, Despina, Dahlman-Wright, Karin, Randeva, Harpal S., Papavassiliou, Athanasios G., Moutsatsou, Paraskevi, Kassi, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506323/
https://www.ncbi.nlm.nih.gov/pubmed/36142876
http://dx.doi.org/10.3390/ijms231810960