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Hydroxychloroquine Effects on THP-1 Macrophage Cholesterol Handling: Cell Culture Studies Corresponding to the TARGET Cardiovascular Trial

Background and Objectives: Cardiovascular (CV) risk is elevated in rheumatoid arthritis (RA). RA patient plasma causes pro-atherogenic derangements in cholesterol transport leading to macrophage foam cell formation (FCF). The TARGET randomized clinical trial compares CV benefits of 2 RA drug regimen...

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Detalles Bibliográficos
Autores principales: Ahmed, Saba, Konig, Justin, Kasselman, Lora J., Renna, Heather A., De Leon, Joshua, Carsons, Steven E., Reiss, Allison B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506397/
https://www.ncbi.nlm.nih.gov/pubmed/36143964
http://dx.doi.org/10.3390/medicina58091287