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Design, Synthesis, and Bioactivities of Novel Tryptophan Derivatives Containing 2,5-Diketopiperazine and Acyl Hydrazine Moieties

Based on the scaffolds widely used in drug design, a series of novel tryptophan derivatives containing 2,5-diketopiperazine and acyl hydrazine moieties have been designed, synthesized, characterized, and evaluated for their biological activities. The bioassay results showed that the target compounds...

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Detalles Bibliográficos
Autores principales: Li, Lili, Yang, Rongxin, Liu, Jianhua, Zhang, Jingjing, Song, Hongjian, Liu, Yuxiu, Wang, Qingmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506431/
https://www.ncbi.nlm.nih.gov/pubmed/36144506
http://dx.doi.org/10.3390/molecules27185758