Myostatin/AKT/FOXO Signaling Is Altered in Human Non-Ischemic Dilated Cardiomyopathy

SIMPLE SUMMARY: Cardiac muscle-specific E3 ligases are enzymes that transfer ubiquitin to proteins to label them for protein degradation through the ubiquitin proteasome system. The E3 ligases MAFbx and MuRF1 are regulated by the myostatin/AKT/FOXO pathway that involves the molecules myostatin, AKT...

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Detalles Bibliográficos
Autores principales: Hildebrandt, Lea, Dieterlen, Maja-Theresa, Klaeske, Kristin, Haunschild, Josephina, Saeed, Diyar, Eifert, Sandra, Borger, Michael A., Jawad, Khalil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506454/
https://www.ncbi.nlm.nih.gov/pubmed/36143454
http://dx.doi.org/10.3390/life12091418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506454/
https://www.ncbi.nlm.nih.gov/pubmed/36143454
http://dx.doi.org/10.3390/life12091418

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