µ-Conotoxins Targeting the Human Voltage-Gated Sodium Channel Subtype Na(V)1.7

µ-Conotoxins are small, potent, peptide voltage-gated sodium (Na(V)) channel inhibitors characterised by a conserved cysteine framework. Despite promising in vivo studies indicating analgesic potential of these compounds, selectivity towards the therapeutically relevant subtype Na(V)1.7 has so far b...

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Detalles Bibliográficos
Autores principales: McMahon, Kirsten L., Tran, Hue N. T., Deuis, Jennifer R., Craik, David J., Vetter, Irina, Schroeder, Christina I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506549/
https://www.ncbi.nlm.nih.gov/pubmed/36136538
http://dx.doi.org/10.3390/toxins14090600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506549/
https://www.ncbi.nlm.nih.gov/pubmed/36136538
http://dx.doi.org/10.3390/toxins14090600

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