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The MEK1/2 Inhibitor ATR-002 (Zapnometinib) Synergistically Potentiates the Antiviral Effect of Direct-Acting Anti-SARS-CoV-2 Drugs

The coronavirus disease 2019 (COVID-19) represents a global public health burden. In addition to vaccination, safe and efficient antiviral treatment strategies to restrict the viral spread within the patient are urgently needed. An alternative approach to a single-drug therapy is the combinatory use...

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Detalles Bibliográficos
Autores principales: Schreiber, André, Ambrosy, Benjamin, Planz, Oliver, Schloer, Sebastian, Rescher, Ursula, Ludwig, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506552/
https://www.ncbi.nlm.nih.gov/pubmed/36145524
http://dx.doi.org/10.3390/pharmaceutics14091776