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Functional architecture of pancreatic islets identifies a population of first responder cells that drive the first-phase calcium response
Insulin-secreting β-cells are functionally heterogeneous. Whether there exist cells driving the first-phase calcium response in individual islets, has not been examined. We examine “first responder” cells, defined by the earliest [Ca(2+)] response during first-phase [Ca(2+)] elevation, distinct from...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506623/ https://www.ncbi.nlm.nih.gov/pubmed/36099294 http://dx.doi.org/10.1371/journal.pbio.3001761 |