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Excitatory and inhibitory effects of HCN channel modulation on excitability of layer V pyramidal cells

Dendrites of cortical pyramidal cells are densely populated by hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, a.k.a. I(h) channels. I(h) channels are targeted by multiple neuromodulatory pathways, and thus are one of the key ion-channel populations regulating the pyramidal cell...

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Detalles Bibliográficos
Autores principales: Mäki-Marttunen, Tuomo, Mäki-Marttunen, Verónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506642/
https://www.ncbi.nlm.nih.gov/pubmed/36099307
http://dx.doi.org/10.1371/journal.pcbi.1010506