PLK4 drives centriole amplification and apical surface area expansion in multiciliated cells

Multiciliated cells (MCCs) are terminally differentiated epithelia that assemble multiple motile cilia used to promote fluid flow. To template these cilia, MCCs dramatically expand their centriole content during a process known as centriole amplification. In cycling cells, the master regulator of ce...

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Detalles Bibliográficos
Autores principales: LoMastro, Gina M, Drown, Chelsea G, Maryniak, Aubrey L, Jewett, Cayla E, Strong, Margaret A, Holland, Andrew Jon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507127/
https://www.ncbi.nlm.nih.gov/pubmed/35969030
http://dx.doi.org/10.7554/eLife.80643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507127/
https://www.ncbi.nlm.nih.gov/pubmed/35969030
http://dx.doi.org/10.7554/eLife.80643

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