Succinylation Inhibits the Enzymatic Hydrolysis of the Extracellular Matrix Protein Fibrillin 1 and Promotes Gastric Cancer Progression

Extracellular matrix (ECM) remodeling is crucial in the regulation of gastric cancer (GC) progression. This work aims to reveal novel posttranslational modifications and their relevant mechanisms in GC. In 3D matrix culture and animal models, it is found that fibrillin 1 (FBN1) expression is increas...

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Detalles Bibliográficos
Autores principales: Wang, Xingyun, Shi, Xiao, Lu, Hongcheng, Zhang, Chen, Li, Xiang, Zhang, Tiancheng, Shen, Jiajia, Wen, Jianfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507347/
https://www.ncbi.nlm.nih.gov/pubmed/35901491
http://dx.doi.org/10.1002/advs.202200546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507347/
https://www.ncbi.nlm.nih.gov/pubmed/35901491
http://dx.doi.org/10.1002/advs.202200546

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