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NFAT1 Orchestrates Spinal Microglial Transcription and Promotes Microglial Proliferation via c‐MYC Contributing to Nerve Injury‐Induced Neuropathic Pain

Peripheral nerve injury‐induced spinal microglial proliferation plays a pivotal role in neuropathic pain. So far, key intracellular druggable molecules involved in this process are not identified. The nuclear factor of activated T‐cells (NFAT1) is a master regulator of immune cell proliferation. Whe...

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Detalles Bibliográficos
Autores principales: Jiang, Bao‐Chun, Ding, Ting‐Yu, Guo, Chang‐Yun, Bai, Xue‐Hui, Cao, De‐Li, Wu, Xiao‐Bo, Sha, Wei‐Lin, Jiang, Ming, Wu, Long‐Jun, Gao, Yong‐Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507349/
https://www.ncbi.nlm.nih.gov/pubmed/35892263
http://dx.doi.org/10.1002/advs.202201300