Sappanone A Alleviated IL-1β-Induced Inflammation in OA Chondrocytes through Modulating the NF-κB and Nrf2/HO-1 Pathways

OBJECTIVE: This study was to examine the anti-inflammatory effect of sappanone A on interleukin- (IL-) 1β-stimulated osteoarthritis (OA) chondrocytes. METHODS: Chondrocytes were pretreated with sappanone A for 2 h before subsequent IL-1β stimulation. The mRNA expression levels of iNOs, COX-2, aggrec...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Zhi, Zhang, Nan-Zhi, Li, Meng, Zhang, Dang-Feng, Ma, Xing, Zhou, Shuang-Li, Qiu, Yu-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507726/
https://www.ncbi.nlm.nih.gov/pubmed/36157214
http://dx.doi.org/10.1155/2022/2380879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507726/
https://www.ncbi.nlm.nih.gov/pubmed/36157214
http://dx.doi.org/10.1155/2022/2380879

Ejemplares similares