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Sappanone A Alleviated IL-1β-Induced Inflammation in OA Chondrocytes through Modulating the NF-κB and Nrf2/HO-1 Pathways
OBJECTIVE: This study was to examine the anti-inflammatory effect of sappanone A on interleukin- (IL-) 1β-stimulated osteoarthritis (OA) chondrocytes. METHODS: Chondrocytes were pretreated with sappanone A for 2 h before subsequent IL-1β stimulation. The mRNA expression levels of iNOs, COX-2, aggrec...
Autores principales: | Zhang, Zhi, Zhang, Nan-Zhi, Li, Meng, Zhang, Dang-Feng, Ma, Xing, Zhou, Shuang-Li, Qiu, Yu-Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507726/ https://www.ncbi.nlm.nih.gov/pubmed/36157214 http://dx.doi.org/10.1155/2022/2380879 |
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