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Visualizing maturation factor extraction from the nascent ribosome by the AAA-ATPase Drg1

The AAA-ATPase Drg1 is a key factor in eukaryotic ribosome biogenesis that initiates cytoplasmic maturation of the large ribosomal subunit. Drg1 releases the shuttling maturation factor Rlp24 from pre-60S particles shortly after nuclear export, a strict requirement for downstream maturation. The mol...

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Detalles Bibliográficos
Autores principales: Prattes, Michael, Grishkovskaya, Irina, Hodirnau, Victor-Valentin, Hetzmannseder, Christina, Zisser, Gertrude, Sailer, Carolin, Kargas, Vasileios, Loibl, Mathias, Gerhalter, Magdalena, Kofler, Lisa, Warren, Alan J., Stengel, Florian, Haselbach, David, Bergler, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507969/
https://www.ncbi.nlm.nih.gov/pubmed/36097293
http://dx.doi.org/10.1038/s41594-022-00832-5