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Renin-angiotensin-system increases phosphorylated tau and Reactive Oxygen Species in human cortical neuron cell line

Alzheimer's Disease (AD) is the most common cause of dementia. AD patients had increased extracellular amyloid β plaques and intracellular hyperphosphorylated tau (p-tau) in neurons. Recent studies have shown an association between the Renin-Angiotensin System (RAS) and AD. The involvement of R...

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Detalles Bibliográficos
Autores principales: De Dios, Luz, Collazo, Camille, Inostroza-Nieves, Yaritza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507985/
https://www.ncbi.nlm.nih.gov/pubmed/36164564
http://dx.doi.org/10.1016/j.bbrep.2022.101355