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Unique and shared systemic biomarkers for emphysema in Alpha-1 Antitrypsin deficiency and chronic obstructive pulmonary disease

BACKGROUND: Alpha-1 Antitrypsin (AAT) deficiency (AATD), the most common genetic cause of emphysema presents with unexplained phenotypic heterogeneity in affected subjects. Our objectives to identify unique and shared AATD plasma biomarkers with chronic obstructive pulmonary disease (COPD) may expla...

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Detalles Bibliográficos
Autores principales: Serban, K.A., Pratte, K.A., Strange, C., Sandhaus, R.A., Turner, A.M., Beiko, T., Spittle, D.A., Maier, L., Hamzeh, N., Silverman, E.K., Hobbs, B.D., Hersh, C.P., DeMeo, D.L., Cho, M.H., Bowler, R.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507992/
https://www.ncbi.nlm.nih.gov/pubmed/36155958
http://dx.doi.org/10.1016/j.ebiom.2022.104262