Deregulation of complement components C4A and CSMD1 peripheral expression in first-episode psychosis and links to cognitive ability

Up-regulation of the complement component 4A (C4A) in the brain has been associated with excessive synaptic pruning and increased schizophrenia (SZ) susceptibility. Over-expression of C4A has been observed in SZ postmortem brain tissue, and the gene encoding for a protein inhibitor of C4A activity,...

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Detalles Bibliográficos
Autores principales: Hatzimanolis, Alex, Foteli, Stefania, Stefanatou, Pentagiotissa, Ntigrintaki, Angeliki-Aikaterini, Ralli, Irene, Kollias, Konstantinos, Nikolaou, Chrysoula, Gazouli, Maria, Stefanis, Nikos C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508018/
https://www.ncbi.nlm.nih.gov/pubmed/35532796
http://dx.doi.org/10.1007/s00406-022-01409-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508018/
https://www.ncbi.nlm.nih.gov/pubmed/35532796
http://dx.doi.org/10.1007/s00406-022-01409-5

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