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Deregulation of complement components C4A and CSMD1 peripheral expression in first-episode psychosis and links to cognitive ability
Up-regulation of the complement component 4A (C4A) in the brain has been associated with excessive synaptic pruning and increased schizophrenia (SZ) susceptibility. Over-expression of C4A has been observed in SZ postmortem brain tissue, and the gene encoding for a protein inhibitor of C4A activity,...
Autores principales: | Hatzimanolis, Alex, Foteli, Stefania, Stefanatou, Pentagiotissa, Ntigrintaki, Angeliki-Aikaterini, Ralli, Irene, Kollias, Konstantinos, Nikolaou, Chrysoula, Gazouli, Maria, Stefanis, Nikos C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508018/ https://www.ncbi.nlm.nih.gov/pubmed/35532796 http://dx.doi.org/10.1007/s00406-022-01409-5 |
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