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Passage number affects differentiation of sensory neurons from human induced pluripotent stem cells

Induced pluripotent stem cells (iPSCs) are a valuable resource for neurological disease-modeling and drug discovery due to their ability to differentiate into neurons reflecting the genetics of the patient from which they are derived. iPSC-derived cultures, however, are highly variable due to hetero...

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Detalles Bibliográficos
Autores principales: Cantor, Erica L., Shen, Fei, Jiang, Guanglong, Tan, Zhiyong, Cunningham, Geneva M., Wu, Xi, Philips, Santosh, Schneider, Bryan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508090/
https://www.ncbi.nlm.nih.gov/pubmed/36151116
http://dx.doi.org/10.1038/s41598-022-19018-6