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CNS myelination requires VAMP2/3-mediated membrane expansion in oligodendrocytes

Myelin is required for rapid nerve signaling and is emerging as a key driver of CNS plasticity and disease. How myelin is built and remodeled remains a fundamental question of neurobiology. Central to myelination is the ability of oligodendrocytes to add vast amounts of new cell membrane, expanding...

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Detalles Bibliográficos
Autores principales: Lam, Mable, Takeo, Koji, Almeida, Rafael G., Cooper, Madeline H., Wu, Kathryn, Iyer, Manasi, Kantarci, Husniye, Zuchero, J. Bradley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508103/
https://www.ncbi.nlm.nih.gov/pubmed/36151203
http://dx.doi.org/10.1038/s41467-022-33200-4