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Acute stress induces severe neural inflammation and overactivation of glucocorticoid signaling in interleukin-18-deficient mice

Interleukin-18 (IL18) is an inflammatory cytokine that is related to psychiatric disorders such as depression and cognitive impairment. We previously found that IL18 deficiency may cause hippocampal impairment, resulting in depression-like behavioral changes. However, the potential role of IL18 in s...

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Detalles Bibliográficos
Autores principales: Yamanishi, Kyosuke, Doe, Nobutaka, Mukai, Keiichiro, Hashimoto, Takuya, Gamachi, Naomi, Hata, Masaki, Watanabe, Yuko, Yamanishi, Chiaki, Yagi, Hideshi, Okamura, Haruki, Matsunaga, Hisato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508168/
https://www.ncbi.nlm.nih.gov/pubmed/36151082
http://dx.doi.org/10.1038/s41398-022-02175-7