Cargando…

Payload distribution and capacity of mRNA lipid nanoparticles

Lipid nanoparticles (LNPs) are effective vehicles to deliver mRNA vaccines and therapeutics. It has been challenging to assess mRNA packaging characteristics in LNPs, including payload distribution and capacity, which are critical to understanding structure-property-function relationships for furthe...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Sixuan, Hu, Yizong, Li, Andrew, Lin, Jinghan, Hsieh, Kuangwen, Schneiderman, Zachary, Zhang, Pengfei, Zhu, Yining, Qiu, Chenhu, Kokkoli, Efrosini, Wang, Tza-Huei, Mao, Hai-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508184/
https://www.ncbi.nlm.nih.gov/pubmed/36151112
http://dx.doi.org/10.1038/s41467-022-33157-4