Activation of the insulin receptor by an insulin mimetic peptide

Insulin receptor (IR) signaling defects cause a variety of metabolic diseases including diabetes. Moreover, inherited mutations of the IR cause severe insulin resistance, leading to early morbidity and mortality with limited therapeutic options. A previously reported selective IR agonist without seq...

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Detalles Bibliográficos
Autores principales: Park, Junhee, Li, Jie, Mayer, John P., Ball, Kerri A., Wu, Jiayi, Hall, Catherine, Accili, Domenico, Stowell, Michael H. B., Bai, Xiao-chen, Choi, Eunhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508239/
https://www.ncbi.nlm.nih.gov/pubmed/36151101
http://dx.doi.org/10.1038/s41467-022-33274-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508239/
https://www.ncbi.nlm.nih.gov/pubmed/36151101
http://dx.doi.org/10.1038/s41467-022-33274-0

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