Co-ingestion of glutamine and leucine synergistically promotes mTORC1 activation

Leucine (Leu) regulates protein synthesis and degradation via activation of mammalian target of rapamycin complex 1 (mTORC1). Glutamine (Gln) synergistically promotes mTORC1 activation with Leu via glutaminolysis and Leu absorption via an antiporter. However, Gln has also been shown to inhibit mTORC...

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Detalles Bibliográficos
Autores principales: Yoshimura, Ryoji, Nomura, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508252/
https://www.ncbi.nlm.nih.gov/pubmed/36151270
http://dx.doi.org/10.1038/s41598-022-20251-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508252/
https://www.ncbi.nlm.nih.gov/pubmed/36151270
http://dx.doi.org/10.1038/s41598-022-20251-2

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