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Sex-biased expression of the TLR7 gene in severe COVID-19 patients: Insights from transcriptomics and epigenomics

There is abundant epidemiological data indicating that the incidence of severe cases of coronavirus disease (COVID-19) is significantly higher in males than females worldwide. Moreover, genetic variation at the X-chromosome linked TLR7 gene has been associated with COVID-19 severity. It has been sug...

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Detalles Bibliográficos
Autores principales: Gómez-Carballa, A., Pardo-Seco, J., Pischedda, S., Rivero-Calle, I., Butler-Laporte, G., Richards, J.B., Viz-Lasheras, S., Martinón-Torres, F., Salas, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508271/
https://www.ncbi.nlm.nih.gov/pubmed/36152884
http://dx.doi.org/10.1016/j.envres.2022.114288