Microbial cytosine deaminase is a programmable anticancer prodrug mediating enzyme: antibody, and gene directed enzyme prodrug therapy

Cytosine deaminase (CDA) is a non-mammalian enzyme with powerful activity in mediating the prodrug 5-fluorcytosine (5-FC) into toxic drug 5-fluorouracil (5-FU), as an alternative directed approach for the traditional chemotherapies and radiotherapies of cancer. This enzyme has been frequently report...

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Detalles Bibliográficos
Autores principales: El-Sayed, Ashraf S.A., Mohamed, Nabil Z., Yassin, Marwa A., Amer, Mahmoud M., El-Sharkawy, Reyad, El-Sayed, Nesma, Ali, Mostafa G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508425/
https://www.ncbi.nlm.nih.gov/pubmed/36164544
http://dx.doi.org/10.1016/j.heliyon.2022.e10660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508425/
https://www.ncbi.nlm.nih.gov/pubmed/36164544
http://dx.doi.org/10.1016/j.heliyon.2022.e10660

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