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Alpha-Synuclein Clearance through Inhibiting Akt/mTOR Pathway by Microfluidic Encapsulated Induced Conjunctival MSCs in a Parkinsonian Model

BACKGROUND & OBJECTIVE: Parkinson's disease (PD) is a progressive neurodegenerative disorder in which the cause is attributed to the alpha-synuclein (α-Syn) accumulation due to the decreased rate of autophagy. Due to the many advantages, mesenchymal stem cells (MSCs), such as the secretion...

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Detalles Bibliográficos
Autores principales: Forouzandeh, Meysam, Bigdeli, Mohammad Reza, Mostafavi, Hossein, Nadri, Samad, Eskandari, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Society of Pathology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508538/
https://www.ncbi.nlm.nih.gov/pubmed/36247500
http://dx.doi.org/10.30699/ijp.2022.553459.2890