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Evolutionary analyses reveal immune cell receptor GPR84 as a conserved receptor for bacteria-derived molecules
The G protein-coupled receptor 84 (GPR84) is found in immune cells and its expression is increased under inflammatory conditions. Activation of GPR84 by medium-chain fatty acids results in pro-inflammatory responses. Here, we screened available vertebrate genome data and found that GPR84 is present...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508565/ https://www.ncbi.nlm.nih.gov/pubmed/36164652 http://dx.doi.org/10.1016/j.isci.2022.105087 |