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Evolutionary analyses reveal immune cell receptor GPR84 as a conserved receptor for bacteria-derived molecules

The G protein-coupled receptor 84 (GPR84) is found in immune cells and its expression is increased under inflammatory conditions. Activation of GPR84 by medium-chain fatty acids results in pro-inflammatory responses. Here, we screened available vertebrate genome data and found that GPR84 is present...

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Detalles Bibliográficos
Autores principales:	Schulze, Amadeus Samuel, Kleinau, Gunnar, Krakowsky, Rosanna, Rochmann, David, Das, Ranajit, Worth, Catherine L., Krumbholz, Petra, Scheerer, Patrick, Stäubert, Claudia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508565/ https://www.ncbi.nlm.nih.gov/pubmed/36164652 http://dx.doi.org/10.1016/j.isci.2022.105087

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