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A novel cysteine protease inhibitor in Baylisascaris schroederi migratory larvae regulates inflammasome activation through the TLR4–ROS–NLRP3 pathway

BACKGROUND: Giant pandas (Ailuropoda melanoleuca) are the obligate host of the parasitic roundworm Baylisascaris schroederi. The infection of giant pandas with B. schroederi is very common. At present, little is known about the mechanism of immune interaction between B. schroederi and the host. As a...

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Detalles Bibliográficos
Autores principales: Xu, Jingyun, Gu, Xiaobin, Xie, Yue, He, Ran, Xu, Jing, Xiong, Lang, Peng, Xuerong, Yang, Guangyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508711/
https://www.ncbi.nlm.nih.gov/pubmed/36151570
http://dx.doi.org/10.1186/s13071-022-05466-6