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Association of Alzheimer’s disease polygenic risk scores with amyloid accumulation in cognitively intact older adults

BACKGROUND: Early detection of individuals at risk for Alzheimer’s disease (AD) is highly important. Amyloid accumulation is an early pathological AD event, but the genetic association with known AD risk variants beyond the APOE4 effect is largely unknown. We investigated the association between dif...

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Detalles Bibliográficos
Autores principales: Luckett, Emma S., Abakkouy, Yasmina, Reinartz, Mariska, Adamczuk, Katarzyna, Schaeverbeke, Jolien, Verstockt, Sare, De Meyer, Steffi, Van Laere, Koen, Dupont, Patrick, Cleynen, Isabelle, Vandenberghe, Rik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508733/
https://www.ncbi.nlm.nih.gov/pubmed/36151568
http://dx.doi.org/10.1186/s13195-022-01079-4