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Association of Alzheimer’s disease polygenic risk scores with amyloid accumulation in cognitively intact older adults
BACKGROUND: Early detection of individuals at risk for Alzheimer’s disease (AD) is highly important. Amyloid accumulation is an early pathological AD event, but the genetic association with known AD risk variants beyond the APOE4 effect is largely unknown. We investigated the association between dif...
Autores principales: | Luckett, Emma S., Abakkouy, Yasmina, Reinartz, Mariska, Adamczuk, Katarzyna, Schaeverbeke, Jolien, Verstockt, Sare, De Meyer, Steffi, Van Laere, Koen, Dupont, Patrick, Cleynen, Isabelle, Vandenberghe, Rik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508733/ https://www.ncbi.nlm.nih.gov/pubmed/36151568 http://dx.doi.org/10.1186/s13195-022-01079-4 |
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