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Reliable assessment of telomere maintenance mechanisms in neuroblastoma

BACKGROUND: Telomere maintenance mechanisms (TMM) are a hallmark of high-risk neuroblastoma, and are conferred by activation of telomerase or alternative lengthening of telomeres (ALT). However, detection of TMM is not yet part of the clinical routine, and consensus on TMM detection, especially on A...

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Detalles Bibliográficos
Autores principales: Meeser, Alina, Bartenhagen, Christoph, Werr, Lisa, Hellmann, Anna-Maria, Kahlert, Yvonne, Hemstedt, Nadine, Nürnberg, Peter, Altmüller, Janine, Ackermann, Sandra, Hero, Barbara, Simon, Thorsten, Peifer, Martin, Fischer, Matthias, Rosswog, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508734/
https://www.ncbi.nlm.nih.gov/pubmed/36153564
http://dx.doi.org/10.1186/s13578-022-00896-2