Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid

Xeno-nucleic acids (XNAs) are synthetic genetic polymers with backbone structures composed of non-ribose or non-deoxyribose sugars. Phosphonomethylthreosyl nucleic acid (pTNA), a type of XNA that does not base pair with DNA or RNA, has been suggested as a possible genetic material for storing synthe...

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Detalles Bibliográficos
Autores principales: Hajjar, Mohammad, Chim, Nicholas, Liu, Chao, Herdewijn, Piet, Chaput, John C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508818/
https://www.ncbi.nlm.nih.gov/pubmed/36124684
http://dx.doi.org/10.1093/nar/gkac792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508818/
https://www.ncbi.nlm.nih.gov/pubmed/36124684
http://dx.doi.org/10.1093/nar/gkac792

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