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Structural insights into the dual activities of the two-barrel RNA polymerase QDE-1

Neurospora crassa protein QDE-1, a member of the two-barrel polymerase superfamily, possesses both DNA- and RNA-dependent RNA polymerase (DdRP and RdRP) activities. The dual activities are essential for the production of double-stranded RNAs (dsRNAs), the precursors of small interfering RNAs (siRNAs...

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Detalles Bibliográficos
Autores principales: Cui, Ruixue, Li, Hao, Zhao, Jin, Li, Xuhang, Gan, Jianhua, Ma, Jinbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508822/
https://www.ncbi.nlm.nih.gov/pubmed/36039765
http://dx.doi.org/10.1093/nar/gkac727