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Trypanosoma brucei histones are heavily modified with combinatorial post-translational modifications and mark Pol II transcription start regions with hyperacetylated H2A

Trypanosomes diverged from the main eukaryotic lineage about 600 million years ago, and display some unusual genomic and epigenetic properties that provide valuable insight into the early processes employed by eukaryotic ancestors to regulate chromatin-mediated functions. We analysed Trypanosoma bru...

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Detalles Bibliográficos
Autores principales: Maree, Johannes P, Tvardovskiy, Andrey, Ravnsborg, Tina, Jensen, Ole N, Rudenko, Gloria, Patterton, Hugh-G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508842/
https://www.ncbi.nlm.nih.gov/pubmed/36095123
http://dx.doi.org/10.1093/nar/gkac759