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Noncanonical Role of Telomerase in Regulation of Microvascular Redox Environment With Implications for Coronary Artery Disease

Telomerase reverse transcriptase (TERT) (catalytic subunit of telomerase) is linked to the development of coronary artery disease (CAD); however, whether the role of nuclear vs. mitchondrial actions of TERT is involved is not determined. Dominant-negative TERT splice variants contribute to decreased...

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Detalles Bibliográficos
Autores principales: Ait-Aissa, K, Norwood-Toro, L E, Terwoord, J, Young, M, Paniagua, L A, Hader, S N, Hughes, W E, Hockenberry, J C, Beare, J E, Linn, J, Kohmoto, T, Kim, J, Betts, D H, LeBlanc, A J, Gutterman, D D, Beyer, A M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508843/
https://www.ncbi.nlm.nih.gov/pubmed/36168588
http://dx.doi.org/10.1093/function/zqac043