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Rotavirus RNA chaperone mediates global transcriptome-wide increase in RNA backbone flexibility

Due to genome segmentation, rotaviruses must co-package eleven distinct genomic RNAs. The packaging is mediated by virus-encoded RNA chaperones, such as the rotavirus NSP2 protein. While the activities of distinct RNA chaperones are well studied on smaller RNAs, little is known about their global ef...

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Detalles Bibliográficos
Autores principales: Coria, Aaztli, Wienecke, Anastacia, Knight, Michael L, Desirò, Daniel, Laederach, Alain, Borodavka, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508848/
https://www.ncbi.nlm.nih.gov/pubmed/36062555
http://dx.doi.org/10.1093/nar/gkac738