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Human Thg1 displays tRNA-inducible GTPase activity
tRNA(His) guanylyltransferase (Thg1) catalyzes the 3′-5′ incorporation of guanosine into position -1 (G-1) of tRNA(His). G-1 is unique to tRNA(His) and is crucial for recognition by histidyl-tRNA synthetase (HisRS). Yeast Thg1 requires ATP for G-1 addition to tRNA(His) opposite A73, whereas archaeal...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508852/ https://www.ncbi.nlm.nih.gov/pubmed/36107775 http://dx.doi.org/10.1093/nar/gkac768 |