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DDX17 modulates the expression and alternative splicing of genes involved in apoptosis and proliferation in lung adenocarcinoma cells

BACKGROUND: The DEAD-box RNA-binding protein (RBP) DDX17 has been found to be involved in the tumorigenesis of many types of cancers. However, the role of DDX17 in lung adenocarcinoma (LUAD) remains unclear. METHODS: We silenced DDX17 expression in A549 LUAD cells by small interfering RNA (siRNA). C...

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Detalles Bibliográficos
Autores principales: He, Cheng, Zhang, Gan, Lu, Yanhong, Zhou, Jingyue, Ren, Zixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508879/
https://www.ncbi.nlm.nih.gov/pubmed/36164607
http://dx.doi.org/10.7717/peerj.13895