IRF7-deficient MDCK cell based on CRISPR/Cas9 technology for enhancing influenza virus replication and improving vaccine production

The influenza virus is a cause of seasonal epidemic disease and enormous economic injury. The best way to control influenza outbreaks is through vaccination. The Madin-Darby canine kidney cell line (MDCK) is currently approved to manufacture influenza vaccines. However, the viral load from cell-base...

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Detalles Bibliográficos
Autores principales: Mayuramart, Oraphan, Poomipak, Witthaya, Rattanaburi, Somruthai, Khongnomnan, Kritsada, Anuntakarun, Songtham, Saengchoowong, Suthat, Chavalit, Tanit, Chantaravisoot, Naphat, Payungporn, Sunchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508885/
https://www.ncbi.nlm.nih.gov/pubmed/36164603
http://dx.doi.org/10.7717/peerj.13989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508885/
https://www.ncbi.nlm.nih.gov/pubmed/36164603
http://dx.doi.org/10.7717/peerj.13989

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